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More info
You can access this
clinical trial
if you have
Skull Pin Insertion or Short Duration Analgesia
and you are
between 20 and 75
years old
The phase for this study is not defined.
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The purpose

Skull pin insertion during craniotomies is a brief, intensely stimulating, painful stimuli occurring during the conduct of a neurosurgical or spine anesthetic. Remifentanil is an ultra short acting opioid that has been successfully used to blunt hemodynamic responses in a wide variety of clinical scenarios. It is our intention to ascertain the optimal dose for blunting the hemodynamic response to skull pin insertion using remifentanil.

Provided treatments

  • Drug: Remifentanil

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01056224. The sponsor of the trial is University Health Network, Toronto and it is looking for 72 volunteers for the current phase.
Official trial title:
The Dose Effects of Remifentanil Boluses on the Hemodynamic Response to Skull Pin Insertion.