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Your journey
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3Review
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More info
You can access this
clinical trial
if you have
Diabetes Mellitus, Type 2 or Adult
and you are
between 18 and 65
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This is a Phase 1 pharmacokinetic, pharmacodynamic study to understand the manner in which the body responds to, as well as how the drug is handled by the body, with once vs twice daily dosing of ertugliflozin (PF-04971729, MK-8835) in participants with type 2 diabetes.

Provided treatments

  • Drug: Ertugliflozin 2 mg single dose
  • Drug: Ertugliflozin 2 mg split into twice daily
  • Drug: Ertugliflozin 4 mg single dose
  • Drug: Ertugliflozin 4 mg split into twice daily
  • Drug: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01054300. The sponsor of the trial is Merck Sharp & Dohme Corp. and it is looking for 52 volunteers for the current phase.
Official trial title:
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, 2-Period, Cross-Over Single Day Evaluation Of The Pharmacokinetic-Pharmacodynamic Effect Of Once And Twice Daily Oral Administration Of PF-04971729 In Patients With Type 2 Diabetes Mellitus