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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Fragile X Syndrome
and you are
between 42 and 16
years old
The phase for this study is not defined.
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The purpose

This is a single center study at the UC Davis MIND Institute in patients age 3.5-16 years of age with fragile X syndrome (FXS), funded by a National Fragile X Foundation Grant. It is a controlled trial of minocycline, an antibiotic commonly used in children for infection or for treatment of neurodegenerative disorders. We are investigating its use in FXS because it lowers matrix metalloproteinase 9 (MMP9) levels, which are high in FXS, and it also strengthens brain connections in the animal models of FXS. We hypothesize that minocycline will likely be helpful for language, behavior and/or cognition in fragile X patients.

Provided treatments

  • Drug: minocycline hydrochloride
  • Drug: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01053156. The sponsor of the trial is University of California, Davis and it is looking for 66 volunteers for the current phase.
Official trial title:
Randomized Double-Blind Controlled Cross Over Trial of Minocycline in Children With Fragile X Syndrome