- Noninvasive cardiac stress testing is imperfect. Inconclusive test results generate
further expensive testing.
- In patients with known or suspected coronary artery disease, both computed tomography
(CT) and magnetic resonance imaging (MRI) have been shown to provide suitable results
for detecting the disease. However, both types of scans have limitations in their
usefulness, and it is not known whether one is preferable in either accuracy or
- To determine the accuracy and cost-effectiveness of CT and MRI in subjects with a prior
inconclusive heart stress test.
- Patients 18 years of age and older who have had an inconclusive heart stress test within
the past 90 days.
- A blood test will be obtained prior to both heart tests. This will require less than a
teaspoon of blood.
- A CT scan will be performed, accompanied by beta blocker medications (to slow heart
rate) or nitroglycerin (to enlarge blood vessels) to improve picture quality, as needed.
- An MRI scan will be performed. Scans will be taken before, during, and after the patient
receives vasodilators (to increase blood flow to the coronary arteries and detect
blockages in heart blood vessels).
- Heart rate and function will be monitored with an electrocardiogram.