Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research (EISNER)
is a multi-study research program being conducted at Cedars-Sinai Medical Center.
The principal objective of this randomized trial (referred to as "Study 1") is to assess
whether coronary artery calcium (CAC) scanning provides clinical benefit thus improving
patient outcomes in asymptomatic subjects with intermediate coronary artery disease (CAD)
risk. Additionally, the study is designed to assess the value of combining the CAC scan with
the Framingham risk score (FRS) and measurements of serum or plasma biomarkers to predict