Actinic keratoses on the face are often numerous and widespread. The application of
Methylaminolevulinate (MAL) on individual lesions followed by the application of a plastic
film on each lesion is difficult and takes time for subjects with many actinic keratoses. The
waiting period of 3 hours between MAL cream application and red light exposure is also long
for patients. The goal of this study is to evaluate the safety and efficacy of photodynamic
therapy (PDT) with MAL with a shorter cream application time (90 minutes) and when MAL is
applied on the entire face without the plastic film.