The objective of this single-arm, prospective study is to perform annual mammography and MRI
breast cancer screening in women who underwent mantle-field irradiation between 1970-1995 at
M. D. Anderson Cancer Center in order to compare the ability of MRI and standard mammography
to identify breast cancer. In addition, we will determine whether the combination of breast
MRI and mammography identifies smaller, earlier-stage tumors, which would lead to improved
cure rates. We will also take the opportunity to determine the incidence and stage of breast
cancer in this high-risk cohort.