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More info
You can access this
clinical trial
if you have
Phenylketonuria
and you are
between 16 and 55
years old
2
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

The purpose of this study is to evaluate whether weekly injections of phenylalanine ammonia lyase (rAvPAL-PEG) can reduce blood phenylalanine concentrations in PKU subjects and whether repeated administration is safe.

Provided treatments

  • Drug: rAvPAL-PEG
Tris trial is registered with FDA with number: NCT00925054. The sponsor of the trial is BioMarin Pharmaceutical and it is looking for 40 volunteers for the current phase.
Official trial title:
Phase 2, Open-Label Dose-Finding Study to Evaluate the Safety, Efficacy, and Tolerability of Multiple Subcutaneous (SC) Doses of rAvPAL-PEG in Subjects With PKU