- Researchers are greatly interested in knowing more about the long-term effects of
various treatments for cancers such as Hodgkin's disease, particularly from those who
have lived 20 to 30 years after treatment.
- Patients who were treated at the National Institutes of Health (NIH) may have undergone
different treatments for which more long-term information is needed.
- To examine the body systems of long-term survivors of Hodgkin's disease to see if there
are any long- term consequences of treatment for Hodgkin's disease.
- To learn more about the long-term effects of cancer treatments.
- Survivors of Hodgkin's disease who were previously treated at the NIH.
- Participants must be at least 18 years of age.
- Participants will need to sign consent forms to allow researchers to obtain
documentation of medical history, including prior treatment for Hodgkin's disease and
prior NIH treatment, including protocol number, where applicable:
- Pertinent medical records, pathology reports, and radiographic imaging studies will be
- Primary care physician's name, address, and other contact information are also required.
- Evaluations during the assessment period:
- Complete physical examination.
- Laboratory studies of blood, urine, and stool samples.
- Radiologic evaluations, including computerized tomography (CT) and magnetic resonance
imaging (MRI) scans for all participants and mammograms for females.
- Cardiac evaluation, vascular studies, and pulmonary studies to measure heart and lung
function, and digestive tests to measure stomach and intestinal function.
- Neurocognitive testing to measure brain function.
- Optional skin biopsy.
- Participants will be asked to complete questionnaires assessing current quality of life
and daily living skills.