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The purpose

Background: - Tumors depend on blood vessels to provide the nourishment that allows them to grow. - Thyroid, parathyroid, adrenal gland and pancreatic neuroendocrine tumors are among the tumors that contain the most blood vessels. Thus, endocrine tumors are important for the study of new blood vessel formation in tumors. Objectives: -To obtain tissues from endocrine tumors for examination to determine how they differ from normal tissue. Eligibility: -Patients who are scheduled for surgery to remove an endocrine tumor, those in or around the thyroid, parathyroid, adrenal gland, pancreas, or any neuroendocrine tissue. Design: - Tissues will be obtained from patients during surgery to remove thyroid, parathyroid, adrenal, pancreas, or neuroendocrine tumors. - About 400 patients will be enrolled in the study over a period of 5 years.
Tris trial is registered with FDA with number: NCT00923780. The sponsor of the trial is National Cancer Institute (NCI) and it is looking for 400 volunteers for the current phase.
Official trial title:
Prospective Evaluation of Tumor Angiogenesis in Endocrine Neoplasms