The investigators performed a prospective study, in order to assess the feasibility and
safety of restricting antimalarials to rapid diagnostic test (RDT)-confirmed cases in
children aged 5 to 15 years-old
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Full eligibility criteria for NCT00913146
Ages eligible for Study
5 Years to 15 Years
Genders eligible for Study
Accepts Healthy Volunteers
Inclusion Criteria in the index group:
School children aged 5 to 15 years.
Tympanic temperature at 37.8°C or above, or if a history of fever in the preceding 24 hours was reported.
A negative malaria (Paracheck® Plasmodium falciparum) RDT.
Asymptomatic children were screened for the Control Group on gender, age, week of inclusion. The first child with a negative RDT and for whom an informed consent was obtained, was included in the CG.
Adequate malaria treatment within a month prior screening.
All locations for NCT00913146
Centre de Santé de Commune
View full eligibility
Tris trial is registered with FDA with number: NCT00913146. The sponsor of the trial is Institut de Recherche pour le Developpement and it is looking for 484 volunteers for the current phase.
Official trial title: Can Treatment of Malaria be Restricted to Parasitologically Confirmed Malaria? A School-Based Prospective, Exposed/Non Exposed to Fever, Study in Benin.
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