Title of Study: Sentinel node biopsy following neoadjuvant chemotherapy in biopsy proven node
positive breast cancer.
Objectives of the study:
1. Evaluate the accuracy of sentinel node biopsy in breast cancer patients presenting with
positive nodal disease, proven by ultrasound guided fine needle aspiration, following
1. Evaluate the technical success of sentinel node biopsy following neoadjuvant
2. Evaluate the accuracy of clinical examination and ultrasound examination of the axilla
in identifying the presence of residual disease in the axilla following neoadjuvant
chemotherapy in biopsy proven node positive breast cancer patients.
Number of patients:
N = 300
Patients with unresected breast cancer that are eligible for neoadjuvant chemotherapy that
present with biopsy proven positive axillary nodes.
From February 2009 to February 2012 - 3 years