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More info
You can access this
clinical trial
if you have
Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery or Aortic Root or Ascending Aortic Aneurysm Repair Surgery
and you are
over 18
years old
2
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

The purpose of the present research study is to investigate the pharmacokinetics, as well as safety, tolerability and pharmacodynamics of different ascending dosing regimens of AP214 in patients undergoing cardiac surgery. AP214, the investigational drug, is being developed to potentially prevent post-surgical kidney injury after thoracic aortic aneurysm repair.

Provided treatments

  • Drug: AP214
  • Drug: Placebo
Tris trial is registered with FDA with number: NCT00903604. The sponsor of the trial is Action Pharma A/S and it is looking for 42 volunteers for the current phase.
Official trial title:
Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery