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More info
You can access this
clinical trial
if you have
Intermittent Hypoxia
and you are
between 18 and 40
years old
-
The phase for this study is not defined.
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The purpose

Rehabilitation approaches introduce a stimulus to a motor system, with the goal to enhance motor function to patients. For example, exposure to brief and intermittent episodes of mild hypoxia has shown to strengthen synaptic pathways to respiratory and skeletal muscle motor neurons. In humans with spinal cord injury, exposure to intermittent hypoxia (IH) alone or in combination with rehabilitative strategies has shown enhanced motor function. Another strategy known as inspiratory threshold loading, which involves breathing against pressure threshold loads, results in improved inspiratory muscle strength. Although there is evidence supporting the use of IH alone or in combination with other rehabilitative strategies in improving motor function in humans, the impact of exposure to IH or IH with inspiratory threshold loading on inspiratory muscle function and ventilation in humans is unknown.

Provided treatments

  • Other: Intermittent Hypoxia
  • Other: Inspiratory Threshold Loading
  • Other: Sham Intermittent Hypoxia
Tris trial is registered with FDA with number: NCT03029559. The sponsor of the trial is University of Florida and it is looking for 22 volunteers for the current phase.
Official trial title:
Intermittent Hypoxia and Inspiratory Threshold Loading as Strategies to Enhance Inspiratory Muscle Function