Complex oro-facial pain is a poorly diagnosed and poorly treated cause of significant
suffering and disability. This study will explore the ability of fMRI to identify patients
with complex oro-facial pain who respond to transcranial magnetic stimulation therapy.
1. To establish baseline patterns of MRI in patients with chronic oro-facial pain without a
definitive etiologic diagnosis.
2. To estimate the rate of treatment success of transcranial stimulation of the primary
motor cortex (M1) in these patients.
3. To identify post-treatment MRI patterns that are associated with treatment success.