This study evaluates the efficacy and tolerability of treatment for T-lymphoblastic lymphoma
(T-LBL) according to modified BFM-95 regimen for acute lymphoblastic leukemia.
Drug: protocol M
Drug: maintenance therapy
Drug: Intrathecal (IT)
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Full eligibility criteria for NCT02396043
Ages eligible for Study
18 Years to 65 Years
Genders eligible for Study
Accepts Healthy Volunteers
Ann Arbor stage IEto stage IVE
at lease one measurable lesion
receive no chemotherapy or radiotherapy before
Adequate renal function (eg, serum creatinine≤1.5 mg/dL and creatinine clearance ≥50 mL minute), and hepatic function (e.g, total bilirubin≤ 2 times the upper limit of normal and aspartate and alanine transaminase levels ≤ 3 times the upper limit of normal)
mismatch the inclusion criteria
systematic central nervous system involvement, previous or concomitant malignancies and any coexisting medical problems that could cause poor compliance with the study protocol.
All locations for NCT02396043
Sun Yat-sen University Cancer Center
GuangZhou, Guangdong, China, 510060
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View full eligibility
Tris trial is registered with FDA with number: NCT02396043. The sponsor of the trial is Sun Yat-sen University and it is looking for 50 volunteers for the current phase.
Official trial title: Modified BFM-95 Regimen for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults:a Prospective Phase II Study
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