The purpose of this study is to evaluate the incidence, prevalence, clinical characteristics
and prognosis of Crohn's disease and ulcerative colitis over time in a district of Seoul,
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Full eligibility criteria for NCT01731665
Ages eligible for Study
Genders eligible for Study
Accepts Healthy Volunteers
Definite cases of CD and UC Patients are diagnosed with CD if they meet at least 2 of the following criteria:
clinical history of abdominal pain, weight loss, malaise, diarrhea, and/or rectal bleeding
endoscopic findings of mucosal cobblestoning, linear ulceration, skip areas, or perianal disease
radiologic findings of stricture, fistula, mucosal cobblestoning, or ulceration
macroscopic appearance of bowel wall induration, mesenteric lymphadenopathy, and
"creeping fat" at laparotomy
pathologic findings of transmural inflammation and/or epithelioid granulomas Only patients who meet these criteria for at least 2 months are included. Patients are diagnosed with UC only if all 3 of the following criteria are present
a typical history of diarrhea or blood and pus or both in the stool for longer than 4 weeks
a typical sigmoidoscopic or colonoscopic picture with diffusely granular, friable, or ulcerated mucosa without rectal sparing or skip lesions or radiological signs of characteristic continuous granular or ulcerated mucosa
characteristic histopathological signs of inflammation on biopsy
Ethnic groups other than Korean
All locations for NCT01731665
Korea, Republic of (1)
Asan Medical Center
Seoul, Korea, Republic of, 138-736
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Tris trial is registered with FDA with number: NCT01731665. The sponsor of the trial is Asan Medical Center and it is looking for 2000 volunteers for the current phase.
Official trial title: Epidemiology of Inflammatory Bowel Disease in the Songpa-Kangdong District, Seoul, Korea.
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