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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Vitamin B12 Deficiency
and you are
between 18 and 42
years old
The phase for this study is not defined.
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The purpose

Folic acid, a form of the vitamin folate, is added to grain products in Canada to help reduce birth defects. Folic acid is the synthetic form of folate and is very stable (doesn't break down) when added to foods. There are emerging health concerns about chronic folic acid consumption. Recently another more natural form of folate, L-5-methyltetrahydrofolate (L-MTHF) has become available. The investigators plan to conduct a randomized trial in women to determine if supplements containing L-MTHF consumed over three months raises blood folate levels as much as supplements containing folic acid. The investigators hypothesize that L-MTHF will increase red cell folate over 12 weeks to same extent as equimolar folic acid.

Provided treatments

  • : L-5-methyltetrahydrofolate (Metafolin ®)
  • : folic acid
  • : Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01584050. The sponsor of the trial is University of British Columbia and it is looking for 150 volunteers for the current phase.
Official trial title:
Relative Bioavailability of Folic Acid and L-5-Methlytetrahydrofolate