The objectives of this study are to evaluate the effects of VX-770 on Midazolam and
Rosiglitazone, and the effect of Fluconazole on VX-770.
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Locations near you
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Full eligibility criteria for NCT01060566
Ages eligible for Study
18 Years to 55 Years
Genders eligible for Study
Accepts Healthy Volunteers
Subjects must be male or female and between 18 and 55 years of age.
Subjects must be judged to be in good health.
Subjects must have a body mass index (BMI) from 18 to 30 kg/m2.
History of any illness that, in the opinion of the investigator or the subject's general practitioner, might confound the results of the study or pose an additional risk in administering study drug(s) to the subject.
Subjects who have human immunodeficiency virus (HIV), hepatitis C, or active hepatitis B.
Female subjects and female partner(s) of male subjects who are pregnant, nursing, or planning to become pregnant during the study or within 90 days of the last dose of study drug.
History of cardiovascular disease, hypoglycemia, or edema.
All locations for NCT01060566
United States (1)
Covan CRU, Inc.
Daytona Beach, Florida, United States, 32117
View full eligibility
Tris trial is registered with FDA with number: NCT01060566. The sponsor of the trial is Vertex Pharmaceuticals Incorporated and it is looking for 24 volunteers for the current phase.
Official trial title: An Open-Label Phase 1 Study to Examine the Effect of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770 in Healthy Subjects
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