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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Type 2 Diabetes or Prediabetes
and you are
between 20 and 65
years old
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

Chronically elevated free fatty acids impair insulin sensitivity and insulin secretion (ie lipotoxicity) by a combination of oxidative stress, endoplasmic reticulum (ER) stress and inflammation. This study will test whether alpha-lipoic acid, which has potent antioxidant and anti-inflammatory properties, prevents or ameliorates lipotoxicity.

Provided treatments

  • Drug: alpha lipoic acid

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01056497. The sponsor of the trial is University Health Network, Toronto and it is looking for 15 volunteers for the current phase.
Official trial title:
The Effect of A-lipoic Acid (ALA) on Fatty Acid-induced Impairment of Glucose-stimulated Insulin Secretion