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You can access this
clinical trial
if you have
Sedation During
and you are
over 18
years old
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The phase for this study is not defined.
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The purpose

The aim of this study is to compare the accuracy of the changes in CVI in response to a standardized noxious stimulus during various targeted pseudo-steady-state concentrations of remifentanil and various steady state level of BIS as guided by propofol effect compartment controlled TCI (closed-loop).

Provided treatments

  • Drug: propofol + remifentanil 0 ng/ml
  • Drug: propofol + remifentanil 2 ng/ml
  • Drug: propofol + remifentanil 4 ng/ml
  • Drug: propofol + remifentanil 6 ng/ml
  • Drug: propofol + remifentanil 0 ng/ml
  • Drug: propofol + remifentanil 2 ng/ml
  • Drug: propofol + remifentanil 6 ng/ml
  • Drug: propofol + remifentanil 6 ng/ml
  • Drug: propofol + remifentanil 0 ng/ml
  • Drug: propofol + remifentanil 2 ng/ml
  • Drug: propofol + remifentanil 4 ng/ml
  • Drug: propofol + remifentanil 6 ng/ml

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01053611. The sponsor of the trial is University Medical Center Groningen and it is looking for 140 volunteers for the current phase.
Official trial title:
Changes in a Composite Variability Index (CVI) and Bispectral Index (BIS) in Response to Standardized Pain Stimuli During Propofol Remifentanil Infusion