The purpose of this study is to compare the safety and effectiveness of Azelaic Acid Gel to
Hydroquinone Cream in the treatment of melasma.
Drug: azelaic acid gel
Drug: hydroquinone cream
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Locations near you
Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Full eligibility criteria for NCT00927771
Ages eligible for Study
18 Years to 89 Years
Genders eligible for Study
Accepts Healthy Volunteers
must have stable moderate-severe epidermal or mixed melasma involving the face
males and females
persons taking birth control medication, hormone replacement therapy or any other hormone altering medication may participate only if they have not started or stopped the medication within the last 3 months
if the person has only dermal melasma
pregnancy, breastfeeding, a positive pregnancy test in the office or plans to become pregnant
a known allergy or sensitivity ot azelaic acid or hydroquinone
the use of photosensitizing medications (ex. tetracycline) within 3 months of the study.
starting or stopping hormonal medication within 3 months
chemical peels, microdermabrasion, or laser treatment within 6 months
worsening or improving melasma
All locations for NCT00927771
United States (1)
Callender Center for Clinical Research
Mitchellville, Maryland, United States, 20721
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View full eligibility
Tris trial is registered with FDA with number: NCT00927771. The sponsor of the trial is Callender Center for Clinical Research and it is looking for 30 volunteers for the current phase.
Official trial title: Efficacy & Safety of Azelaic Acid 15% Gel vs. Hydroquinone 4% Cream in the Treatment of Melasma
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