This trial is completed!
Search for a recruiting clinical trial for your condition
Your journey
1What's a trial
2Find
3Review
4Get in touch
More info
You can access this
clinical trial
if you have
Renal Transplant Patients, Metabolic Acidosis, Physical Capacity, Bone Disease or Mineral Metabolism
and you are
between 20 and 65
years old
2
This is a second phase trial assessing
efficacy and side effects of the new treatment.
Show me locations

The purpose

Acidosis (accumulation of acid in the body) may be an underrecognized problem in patients after renal transplantation. It may have consequences on physical performance due to negative effects on bone and muscle metabolism. Therefore, the purpose of this study is 1. to determine the status of physical capacity and bone structure in renal transplant patients with metabolic acidosis 2. to study the effect of substituting base equivalents (citrate) on acid/base status of renal transplant patients with acidosis 3. to compare the status of physical capacity and bone structure in renal transplant patients with metabolic acidosis before and after substitution with citrate

Provided treatments

  • Drug: Potassium citrate
  • Drug: Potassium chloride
Tris trial is registered with FDA with number: NCT00913796. The sponsor of the trial is University of Zurich and it is looking for 30 volunteers for the current phase.
Official trial title:
Metabolic Acidosis and Its Impact on Mineral Metabolism and Physical Performance in Renal Transplant Patients