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More info
You can access this
clinical trial
if you have
and you are
between 7 and 30
years old
This is an observational trial.
You are contributing to medical knowledge about your condition.
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The purpose

Vocal cord dysfunction is a rare clinical picture. It is labeled as a sudden and threatening dyspnea. Patients with VCD may also present cough, hoarseness, wheezing, and chest tightness, but an inspiratory stridor is the most common symptom. For this reason, such patients are often misdiagnosed with refractory asthma, because of poor response to steroids and bronchodilators. Diagnosis is suspected on clinical grounds and is confirmed with laryngoscopy. The therapy consists of education, speech therapy and if necessary psychotherapy. The purpose of the investigators' study is to characterize children, adolescents, and young adults with VCD, and the evaluation of predictors as atopy, bronchial hyperresponsiveness, and psychiatric features.

Provided treatments

  • Other: Methacholine challenge testing
  • Procedure: Rhino-laryngoscopy
Tris trial is registered with FDA with number: NCT00906867. The sponsor of the trial is Johann Wolfgang Goethe University Hospital and it is looking for 25 volunteers for the current phase.
Official trial title:
Pulmonary Function Test, Bronchial Hyperresponsiveness and Quality of Life in Patients With Vocal Cord Dysfunction (VCD)