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Prospective Study for Prognostic Biomarkers of Nasopharyngeal Carcinoma (NCT03025854)

Guilin Medical University, China
The purpose of this clinical research project is to explore potential biomarkers and validate the predictive and prognostic value of molecular signature in nasopharyngeal carcinoma.
  • Other: laboratory biomarker analysis
    Ages eligible for Study
    all
    Genders eligible for Study
    All
    Accepts Healthy Volunteers
    No
    Inclusion Criteria:
    • Patients with newly histologically confirmed nasopharyngeal carcinoma
    • No evidence of distant metastasis (M0)
    • Written informed consent
    Exclusion Criteria:
    • Treatment with palliative intent
    Objectives:

    Primary: Evaluation of failure-free survival after three years of patients of nasopharyngeal carcinoma.

    Secondary: Evaluation of overall survival after three years of patients of nasopharyngeal carcinoma.

    Outline: This is a multicenter observational study. Tumor tissue specimens are obtained from the Sun Yat-sen University Cancer Center and Affiliated Hospital of Guilin Medical University. The samples are analyzed for biomarkers. The biomarkers are correlated with clinical outcomes (failure-free survival, overall survival, tumor response to treatment, distant metastasis, recurrence and death).

    The aim of the analysis is to explore potential biomarkers and validate the predictive and prognostic value of molecular signature in nasopharyngeal carcinoma. This will lead to the definition of risk groups and stratification of patients and will help to precision medicine of nasopharyngeal carcinoma.

    1 locations

    China (1)
    • Sun Yat-sen University Cancer Center
      not yet recruiting
      Guangzhou, Guangdong, China, 510060
    Status:
    not yet recruiting
    Type:
    Observational
    Phase:
    -
    Start:
    31 December, 2016
    Updated:
    18 January, 2017
    Participants:
    600
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