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The Importance of Metabolomics in Assessing the Quality of Kidney Transplants Retained on a LifePort® Perfusion Machine Before Renal Transplantation (NCT03024229)

Laboratory of Biochemistry, University François Rabelais of TOURS
When the kidneys are perfused on perfusion machines before transplantation, the resistance parameters as well as the histological score on the pre-implantation biopsy participate in the evaluation of the quality of the graft. The metabolomic profile of the infusion fluid could provide additional evidence.
  • Device: LifePort® perfusion machine
    Renal perfusion on LifePort® machine
    Ages eligible for Study
    18 Years and older
    Genders eligible for Study
    All
    Accepts Healthy Volunteers
    No
    Inclusion Criteria:
    • Donors aged 18 years or more in brain death or who died of cardiac arrest collected locally in Tours, associated with the major local recipients of the grafts over the same period.
    Exclusion Criteria:
    • Kidney transplant removed but stored in a static preservative.
    • Kidney grafts of donors aged 18 years or more, removed and not retained on a LifePort® perfusion machine.
    The quality of the renal transplant prior to transplantation is essential for the recovery of graft function in the days following transplantation and its long-term survival. When the kidneys are perfused on perfusion machines before transplantation, the resistance parameters as well as the histological score on the pre-implantation biopsy participate in the evaluation of the quality of the graft. The metabolomic profile of the infusion fluid could provide additional evidence.

    1 locations

    France (1)
    • Urology CHRU-TOURS
      recruiting
      Tours, I&L, France, 37000
    Status:
    recruiting
    Type:
    Interventional
    Phase:
    -
    Start:
    14 March, 2017
    Updated:
    08 May, 2017
    Participants:
    40
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