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Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis (NCT03023241)

To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.
  • Procedure: biopsy
    cold cup bladder biopsies and bladder washings under anesthesia, blood and urine collection
    Ages eligible for Study
    18 Years to 90 Years
    Genders eligible for Study
    Female
    Accepts Healthy Volunteers
    No
    Inclusion Criteria:
    • patient with diagnosed BPS/IC, OAB or healthy controls
    • included healthy controls must have another pelvic surgery planned (e.g. hysterectomy)
    • being able to act and judge
    Exclusion Criteria:
    • unstable endocrinological situation
    • severe illness
    Collection and analyses of bladder biopsies, bladder washings, blood and urine samples of patients with bladder pain syndrome/interstitial cystitis (BPS/IC), overactive bladder syndrome (OAB) and bladder-healthy controls. Analyses include ELISA, RT-qPCR, DNA sequencing, and immunohistochemistry techniques. Differences between patient groups are statistically evaluated.

    1 locations

    Switzerland (1)
    • Cantonal Hospital Frauenfeld
      recruiting
      Frauenfeld, Thurgau, Switzerland, 8501
    Status:
    recruiting
    Type:
    Interventional
    Phase:
    -
    Start:
    30 November, 2004
    Updated:
    12 January, 2017
    Participants:
    300
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